The use of "Microsampling" in small animal safety testing.
Reduce the amount of test substances and costs! It is possible to link toxicity evaluation with blood drug concentration!
Inari Research utilizes the method of "Microsampling," which involves blood collection of 50μL or less, in small animal safety testing. This consideration aligns with the 3Rs (Reduction, Replacement, Refinement). We obtain TK Profiles using toxicology test animals (rats and marmosets). Additionally, we can link toxicity evaluations to blood drug concentrations, reduce the amount of test substances, and lower costs. 【Features】 ■ Consideration for the 3Rs (Reduction, Replacement, Refinement) ■ Obtaining TK Profiles using toxicology test animals (rats and marmosets) ■ Conducting TK on the same satellite animals (mice) ■ Ability to link toxicity evaluations to blood drug concentrations ■ Reduction of test substance amounts and cost savings In Plasma Micro-Sampling (PMS): ■ Blood collection volume reduced to 1/15 to 1/10 ■ Measurement sensitivity increased by 20 times *Please feel free to contact us regarding toxicology test design and the development of high-sensitivity measurement methods.
- Company：イナリサーチ
- Price：Other
